SEROQUEL XR among others, is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. It is also used as a sleep aid due to its sedating effect, but this use is not recommended. It is taken by mouth.
High blood sugar and diabetes have been reported with SEROQUEL XR and medicines like it. If you have diabetes or risk factors such as obesity or a family history of diabetes, your doctor should check your blood sugar before you start taking SEROQUEL XR and also during therapy. If you develop symptoms of high blood sugar or diabetes, such as excessive thirst or hunger, increased urination, or weakness, contact your doctor. Complications from diabetes can be serious and even life threatening.
Increases in triglycerides and in LDL (bad) cholesterol and decreases in HDL (good) cholesterol have been reported with SEROQUEL XR. Your doctor should check your cholesterol levels before you start SEROQUEL XR and during therapy.
Weight gain has been reported with SEROQUEL XR. Your doctor should check your weight regularly.
Tell your doctor about any movements you cannot control in your face, tongue, or other body parts, as they may be signs of a serious condition called tardive dyskinesia (TD). TD may not go away, even if you stop taking SEROQUEL XR. TD may also start after you stop taking SEROQUEL XR.
Other risks include feeling dizzy or lightheaded upon standing, falls (which may cause serious injuries), trouble swallowing, or decreases in white blood cells (which can be fatal). Fever, flu-like symptoms, or any other infection could be a result of a very low white blood cell count. Tell your healthcare provider as soon as possible if you experience any of these.
Before starting treatment, tell your doctor about all prescription and nonprescription medicines you are taking. Also tell your doctor if you have or have had low white blood cell count, seizures, abnormal thyroid tests, high prolactin levels, heart or liver problems, trouble emptying your bladder, enlarged prostate, constipation, increased pressure inside your eyes, or cataracts. An eye exam for cataracts is recommended at the beginning of treatment and every 6 months thereafter.
Since drowsiness has been reported with SEROQUEL XR, you should not participate in activities such as driving or operating machinery until you know that you can do so safely. Avoid becoming overheated or dehydrated while taking SEROQUEL XR. Do not drink alcohol while taking SEROQUEL XR.
Tell your doctor if you are pregnant or intend to become pregnant. Avoid breast-feeding while taking SEROQUEL XR.
The most common side effects are drowsiness, dry mouth, constipation, dizziness, increased appetite, upset stomach, weight gain, fatigue, difficulty moving, disturbance in speech or language, and stuffy nose.
Do not stop taking SEROQUEL XR without talking to your doctor. Stopping SEROQUEL XR suddenly may cause side effects.
This is not a complete summary of safety information. Please discuss the full Prescribing Information with your health care provider.